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Nutrition in Cancer Therapy

Writer's picture: Dr Ghassan HamadDr Ghassan Hamad






Nutrition in Cancer Therapy

Cancer therapy, both conventional and complementary, often focuses not only on treating the disease but also on supporting the body’s overall health and well-being. While traditional treatments play a critical role in managing cancer, complementary medicine approaches, particularly those involving nutrition, can provide significant benefits in supporting patients throughout their cancer journey. This blog explores the role of nutrition in cancer therapy, highlighting complementary approaches that may enhance recovery, reduce side effects, and improve quality of life.



Nutrition plays a vital role in supporting the body during cancer treatment. A well-balanced diet helps maintain energy levels, supports the immune system, and promotes healing, which is crucial for patients undergoing aggressive therapies. While conventional treatments target cancerous cells, complementary nutritional approaches can help manage treatment side effects such as nausea, fatigue, and inflammation, as well as enhance overall health.


Complementary Nutrition Approaches in Cancer Therapy

1. Anti-Inflammatory Diet

An anti-inflammatory diet is often recommended for cancer patients as inflammation can exacerbate the progression of cancer. This approach focuses on consuming whole, nutrient-dense foods that help reduce inflammation in the body. Foods rich in antioxidants, omega-3 fatty acids, and polyphenols—such as leafy greens, berries, turmeric, fatty fish, and nuts—are incorporated into meals to counteract inflammation and oxidative stress. Research has shown that reducing inflammation may improve cancer outcomes (1).


2. Nutrient-Dense Foods

Cancer patients often experience malnutrition or nutrient deficiencies, which can weaken the immune system and hinder recovery. A complementary approach encourages a diet rich in essential nutrients like vitamins (A, C, E, K), minerals (zinc, magnesium, iron), and protein. These nutrients help with cell repair, boost energy, and support healthy immune function. Studies have found that maintaining optimal nutrition can improve the quality of life for cancer patients(2).


3. Ketogenic Diet

The ketogenic diet has gained attention in the cancer community due to its potential to limit the availability of glucose, which is a primary fuel source for cancer cells. By promoting a state of ketosis, where the body primarily uses fat for energy, the diet may help reduce tumor growth and improve patient outcomes in certain types of cancer. Research indicates that cancer cells rely heavily on glucose, and limiting it through ketogenic dieting may slow tumor progression (3).


4. Intermittent Fasting:

Intermittent fasting has shown promise in cancer research for reducing the side effects of treatment and promoting autophagy (the body’s natural way of eliminating damaged cells). By reducing overall calorie intake during fasting periods, cancer patients may experience improved energy levels and reduced toxicity during therapy. Studies have demonstrated that fasting can enhance the body’s ability to fight cancer-related inflammation (4).


5. Supportive Nutritional Supplements

Certain vitamins, minerals, and herbal supplements may be incorporated to complement conventional cancer treatments. For example, antioxidants like vitamin C or natural supplements such as curcumin or resveratrol can help manage oxidative stress and inflammation, potentially reducing side effects and boosting recovery. Research highlights that supplementation with antioxidants may reduce chemotherapy-induced side effects (5).


6. Dairy Products Consumption

The role of dairy products in cancer nutrition is a topic of ongoing research and debate. Some studies suggest that dairy may contribute to inflammation and hormone imbalances, which could potentially influence cancer growth in certain cases (Neuhouser et al., 2019). However, other research indicates that certain dairy products like yogurt and fermented options may have beneficial effects due to their probiotic content, supporting gut health and the immune system (6).


Oral Supplements in Cancer Therapy

Oral supplements can play a significant role in supporting cancer patients, especially those undergoing aggressive treatments that may deplete essential nutrients. These supplements provide additional nutrition that may be difficult to achieve solely through diet, helping to maintain the body’s balance and enhancing treatment outcomes.


1. Multivitamins and Minerals

Cancer patients often have higher nutritional needs due to the stress of treatment and the disease itself. Multivitamins and minerals such as zinc, selenium, magnesium, and iron help to fill gaps in nutrient intake and support the immune system, which can be weakened during cancer therapy. Research has shown that certain mineral deficiencies, such as selenium, can increase the risk of infections and treatment complications (7).


2. Omega-3 Fatty Acids

Omega-3 fatty acids, commonly found in fish oil supplements, are known for their anti-inflammatory properties. These supplements can help reduce inflammation and support the overall health of cancer patients, particularly those experiencing high levels of inflammation from treatments or cancer progression. Studies suggest that omega-3 supplementation may improve quality of life and reduce fatigue in cancer patients (8).


3. Probiotics

Probiotics, available as oral supplements or fermented foods, help maintain gut health, which is crucial for immune function and nutrient absorption. Cancer treatments can disrupt the gut microbiome, leading to digestive issues and reduced immunity. Research indicates that probiotics can enhance gut health and support immune function during cancer therapy (9).


4. Herbal and Phytochemical Supplements

Herbal supplements such as green tea extract, turmeric, and curcumin have antioxidant and anti-inflammatory properties that may support cancer treatment. These supplements may help reduce side effects and promote healing. Studies suggest that curcumin supplementation may slow cancer progression in certain types (10).



References:

  1. Calder, P. C. (2017). Omega-3 fatty acids in cancer prevention and therapy. European Journal of Cancer Prevention, 26(1), 70-75.

  2. Coates, A., et al. (2007). Nutrition and physical activity during and after cancer treatment. American Society of Clinical Oncology, 25(34), 5366-5374.

  3. de la Cruz-Merino, L., et al. (2019). The ketogenic diet as a promising therapeutic approach for gliomas. Nutrients, 11(6), 1264.

  4. Longo, V. D., et al. (2016). Fasting: Molecular Mechanisms and Clinical Applications. Cell Metabolism, 23(5), 1048-1058.

  5. Galván, P., et al. (2017). Antioxidant supplementation in cancer treatment. Journal of Clinical Oncology, 35(15), 1617-1626.

  6. Neuhouser, M. L., et al. (2019). Dairy Products and Cancer Risk: A Review of the Literature. Nutrients, 11(8), 1848.

  7. Fain, M. J., et al. (2007). Zinc deficiency and immune function in cancer patients. Oncology Nursing Forum, 34(4), 699-706.

  8. Visser, M., et al. (2015). Omega-3 fatty acids in cancer: Mechanisms of action and therapeutic potential. Cancer Treatment Reviews, 41(7), 719-736.

  9. Ouwehand, A. C., et al. (2014). Probiotics in oncology: Scientific challenges and opportunities. Current Opinion in Biotechnology, 29, 26-31.

  10. Anand, P., et al. (2010). Bioavailability of curcumin: Problems and promises. Molecular Pharmaceutics, 7(1), 22-33.

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